Proton pump inhibitors are drugs that reduce your gastric secretions. They are used to treat stomach ulcers, heartburn, stomach tumors that secrete acid, and other conditions in which there is too much acid in the stomach. According to research, proton pump inhibitors can also occur in the treatment of type 2 diabetes.
In a study published in World Journal of Diabetes In December 2011, investigators from the Department of Endocrinology and Nutrition at the Miguel Servet Hospital in Spain reviewed hemoglobin A1c levels in 97 volunteers with type 2 diabetes.
More than 55% took proton pump inhibitors ...
- those who took insulin and proton pump inhibitors had HbA1c levels on average 8% lower than insulin alone.
- among those who took other antidiabetic drugs, HbA1c levels were consistently lower in those who took proton pump inhibitors than diabetics who took only antidiabetic drugs.
From the above information, it was concluded that proton pump inhibitors were associated with improved blood sugar control compared to antidiabetic drugs alone.
Stomach ulcers can be a problem in people with diabetes who are vulnerable to bacterial infections called Helicobacter pylori, also known as H. pylori, the bacteria responsible for most ulcers. Bleeding can be a complication.
Proton pump inhibitors include:
- omeprazole, (ецes, Prilos, Tsegyrid)
- lansoprazole, (Prevacid, Zoton)
- dexlansoprazole, (Kapidex, Dexilant)
- esomeprazole, (Nexium, Esotrex)
- pantoprazole, (Protonix, Somac) and
- rabeprazole (Zechin, Nzole-D).
Omeprazole, also known as Prilosec, is not only designed to reduce stomach acids, but in combination with antibiotics, kill the bacteria responsible for causing ulcers. It can be taken one, two or three times a day depending on why this is done. It is available by prescription as well as without a prescription. This is taken within two weeks and the regimen can be repeated after 4 months.
Lansoprazole, also known as Prevacid, is usually taken once a day for 14 days. Like omeprazole, it can be repeated after 4 months.
Dexlansoprazole is taken once a day, usually before meals.
Esomeprazole, or Nexium, is taken once or twice a day, usually one hour before meals.
Pantoprazole or Protonix is taken once or twice a day with or without food.
Rabeprazole, or AcipHex, is taken once a day for 4-8 weeks.
The mild side effects of proton pump inhibitors include diarrhea, nausea, vomiting, and abdominal pain. More serious and, fortunately, rare side effects include palpitations, swelling of the face or tongue, rash, hives, difficulty breathing or swallowing, itching or fever. Tell your doctor if you have a history of liver disease.
Proton pump inhibitors are among the most widely sold drugs in the world and, according to studies conducted on them, are considered effective.
