In recent years, an increasing number of hypertension experts are exploring the best ways to administer BP medicines to achieve the best results. This quest was essentially due to the difficulties associated with prescribing high blood pressure drugs for people who have different circumstances. A brief review, made so far in the possibility of creating a personalized treatment of blood pressure, promised generous benefits that can revolutionize the treatment of blood pressure.
In another study on arterial hypertension, doctors tracked more than 2,100 men and women with high blood pressure for five years. These patients had an average age of 56 years and were divided into two groups. One group was supposed to take antihypertensive drugs at bedtime. The second group was supposed to take medication for hypertension in the morning when they were awakening or at breakfast. Taking hypertension medicine for breakfast is a general recommendation given to patients by doctors all over the world.
Monitoring of blood pressure in these patients was, in fact, an outpatient monitoring of blood pressure, which works around the clock. Blood pressure monitoring was carried out at intervals of 20-30 minutes during the first two days, depending on the time of day at the beginning of the study. Further measurements were carried out at least once a year over the next five years. Ambulatory blood pressure control (ABPM) is necessary in order to give a person blood pressure both during the day and during sleep at night, which is an important period.
Researchers in these studies noted that it is necessary to overestimate the method of administration of drugs AD. A study report notes that those who took at least one of their BP drugs at night were somewhat beneficial. In fact, more than 60% of the group monitored blood pressure for a 24-hour period. This is compared with 53 percent of patients in the group who took the medication in the morning or at breakfast. Taking BP tablets at night was only allowed in one-third of the cardiovascular events that the group that took the tablets in the morning took.
Doctors say that there should be a reason why BP drugs are more effective when taken at night before going to bed. It is noted that BP drugs stop the release of certain chemicals synthesized during sleep. These chemicals increase blood pressure to abnormal levels. Taking pills at night fits somewhat into the body circadian clock, thereby optimizing medications, so to speak. This also leads to undesirable side effects, why some patients refuse medications in the medium term to reduce their blood pressure.
