The active ingredient in medical marijuana, known as 9 tetrahydrocannabinol or THC, is currently being studied for various purposes in various clinical studies. One of the recent effects of THC, which is currently being studied, is its ability to inhibit the growth of tumors, and this discovery could have far-reaching implications for research related to cancer treatment. The results of a study conducted by Salazar et al. which were published in the Journal of Clinical Studies, indicate that THC found in medical hash oil causes autophagy of tumor cells.
Autophagy refers to the process of cell degradation when cells begin to destroy themselves. It is known that MMJ inhibits tumor growth by activating a series of events in cancer cells that trigger their death in a programmed way (also called apoptosis). Medical cannabis has a number of beneficial cannabinoids and other components, and their ability to produce certain physiological changes is also being investigated. A hash oil that is loaded with these useful and interesting cannabinoids, such as 9 THC and others, may contain a response to cancer treatment, as suggested by Spanish researchers who published their data in the British Journal of Cancer.
Their study was intended primarily for the treatment of prostate cancer and the results. 9 THC does not kill cancer cells with enthusiasm and without any discrimination. In fact, the cell death process is extremely targeted and very specific, since THC adopts a cell surface receptor binding mechanism that activates the cellular signaling pathway, thereby causing cell death. Since these changes occur at the cellular level with the participation of various molecular players and factors, scientists were able to use knockout mice and siRNA to understand how the whole process works. In addition to systematic and autophagy, which is one of the most important steps contributing to this process of programmed cell death, the useful biological effects of cannabinoids in combating the symptoms of other chronic diseases and diseases are also successfully developing.
Medical marijuana not only slows the spread and growth of cancer, but also kills them, and its use in the prevention and treatment of intestinal cancer is well documented. Professor Chris Paraskeva in Bristol, whose work is funded by Cancer Research UK, is investigating the cannabinoid anti-cancer properties to treat this type of cancer. All studies were conducted using purified cannabinoid chemicals, rather than cannabis itself, which contains a number of other chemicals. In addition, there is no reliable evidence that smoking MMJ can cure cancer.
Basically there are two types of cannabinoid receptors; CB1 and CB2, which cause a cascade of biological events within them. While the first type is mainly found in the nerve cells of the brain and is responsible for changes in the mental effect of cannabis, the latter is found throughout the body, and it may be the main suspect who causes the biological effects of these cannabinoids to other parts of the body than the brain. Thus, the development of suitable drugs based on the active ingredients that are contained in the hash oil may be important for the treatment of cancer.
